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You are here: Home Administration Chemistry & Biochemistry Department Events 2019 April Biochemistry Seminar: Jorge E. Galán, "Type III secretion machines: bacterial devices for protein delivery into eukaryotic cells"

Biochemistry Seminar: Jorge E. Galán, "Type III secretion machines: bacterial devices for protein delivery into eukaryotic cells"

Jorge E. Galán, Professor of Microbiology, Chair, Department of Microbial Pathogenesis, Yale University, CT, "Type III secretion machines: bacterial devices for protein delivery into eukaryotic cells"
When Apr 17, 2019
from 12:00 PM to 01:00 PM
Where CUNY ASRC Main Auditorium
Contact Name
Contact Phone 212-650-8803
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ABSTRACT

One of the most exciting developments in the field of bacterial pathogenesis during the last two decades has been the discovery that bacterial pathogens utilize specialized nanomachines to deliver bacterial proteins into eukaryotic cells.  These proteins have the capacity modulate a variety of cellular functions for the pathogen’s benefit.  This strategy is widespread in nature since the presence of this type of machines has been detected in many bacteria pathogenic or symbiotic for animals, plants, or insects.  One of this type of machines is known as the Type III Secretion System. The structure and function of the type III secretion machine and its assembly pathway will be discussed.

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