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Endowing Intelligence into Protein Biomaterials Jin Kim Montclare

The Salzberg Chemistry Seminar Series
When Feb 01, 2021
from 01:00 PM to 02:00 PM
Where via Zoom
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Abstract: Inspired by nature’s biopolymers, we engineer artificial protein materials with entirely new properties and function. We employ synthetic and chemical biology to construct our materials and endow them with stimuli-responsiveness. In particular, we have fabricated protein-derived nanomaterials: coiledcoil fibers, helix-elastin block polymers, and supercharged coiled-coil•lipid complexes (or lipoproteoplexes). We investigate the fundamental selfassembly and molecular recognition capabilities of these systems. More importantly, we are able to harness these structure as well as others to interface with small molecule therapeutics, genes, and cells

Biography: Jin Montclare is a Professor in the Chemical and Biomolecular Engineering, Chemistry, Biomaterials and Radiology at New York University. She is performing groundbreaking research in engineering proteins to mimic nature and, in some cases, work better than nature. She exploits nature’s biosynthetic machinery and evolutionary mechanisms to design new artificial proteins. Her lab focuses on two research areas: (1) developing protein biomaterials and (2) engineering functional proteins/enzymes for particular substrates with the aim of targeting human disorders, drug delivery and tissue regeneration. Dr. Montclare leads the multidisciplinary Convergence of Innovation and Entrepreneurship (CIE) Institute. She has garnered several awards and honors including but not limited to the Air Force Young Investigator Award, ACS Women Chemists Committee Rising Star Award, AIMBE College of Fellows, the AAAS Leshner Fellowship on Human Augmentation and recently inducted into the National Academy of Inventors.

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