Karen Hubbard

Research Interests:

Karen Hubbard is a molecular biologist, who studies gene expression during cellular aging. Her research focuses on RNA metabolism during aging and the relationship between cell death (apoptosis), cancer and aging. Dr. Hubbard teaches graduate and undergraduate level courses in the Biology Department. She also heads a collaborative partnership between CCNY and Memorial Sloan-Kettering Cancer Center (see link above). This partnership focuses on cancer research, training and health disparities.

Recent Publications:  

Zhou, D., Xu, G., Ghandhi, S. and Hubbard, K. (2002) Modulation of the expression of p16INK4a and p14ARF by hnRNP A1 and A2 RNA binding proteins: Implications for cellular senescence. J. Cell Phys. 193:19-25.

Seifer, D.B., DeJesus, V., and Hubbard, K. (2002) Mitochondrial deletions in lutenized granulosa cells as a function of age in women undergoing in vitro fertilization. Fertilization & Sterility. 78:1046-1048.

DeJesus, V., Rios, I., Davis, C. , Chen, Y., Calhoun, D., Zakeri, Z. and Hubbard, K. (2002) Induction of apoptosis in human senescent human fibroblasts. Exp. Cell Res. 274:92-99.

Ji, F., Pierre, Z., Liu, S., Hwang, B.-J., Hill, H., Hubbard, H., and Steinberg, M.L. (2006) Novel UVB-induced mitochondrial deletions in human epithelial cells irradiated in vitro. J. Photochem. Photobiol. 184:340–346.

Hubbard, K., Steinberg, M.L., Hill, H., and Orlow, I. (2008) Mitochondrial DNA deletions in skin from melanoma patients. Ethnicity and Disease. 18:S2-38.

Steinberg, M.L., Hubbard, K., Utti, C., Hwang, B.-J.,Clas, B., Hill, H., Orlow, I. (2008)  Patterns of persistent DNA damage associated with sun exposure and GSTM1 genotype in - melanoma patients. Photochem. Photobiol. In Press.