This group bridges Chemistry, Physics, and Biomedical Engineering at CCNY. Our research efforts have a good balance of theory (Gunner, Green, Ceruso, Lazaridis) and experiment (Stark, Ghose, Koder, DeCarlo; Gilchrist and Tu in Bioengineering; Gottlieb at the Sophie Davis Medical School).
The computational group focuses on proteins in membranes, featuring strength in developing new methods of treating electrostatic interactions in proteins and implicit modeling of lipid membranes. The experimental group has specialties in solution- and solid-state NMR and cyroelectron microscopy, benefitting from excellent instrumentation at both CCNY and the nearby New York Structural Biology Center (NYSBC).
Research interests range from solving the structures of proteins which are important in cell signaling and RNA synthesis (Ghose) to using solid-state NMR to study complex structures such as the protective surfaces of plants (Stark) to building proteins from scratch to understand the rules for folding and function (Koder).
The computational biophysics group uses computational methods to understand the structure and function of biological macromolecules. Specific interests include the development of methods for the prediction of titration properties of proteins (Marilyn Gunner), the use of ab initio computations to explore the role of water in the gating of ion channels (Michael Green), modeling the interaction of proteins with biological membranes (Themis Lazaridis), and understanding the mechanics of transmembrane signaling receptors (Marco Ceruso).
In addition to collaborating scientifically with each other, the CCNY Molecular Biophysics group shares intellectual and equipment resources with researchers in CCNY's NIH-sponsored Research Centers in Minority Institutions (RCMI) program and leads CUNY's Institute for Macromolecular Assemblies (MMA). Vigorous research collaborations are maintained with the world-class NYSBC, which operates high-field NMR and cryoelectron microscopes located on the CCNY campus. Our research-inspired educational initiatives are pursued with partners that include the CCNY Pathways Bioinformatics Center and CUNY's College Now program |
Chemistry Seminar - Synthesis and Luminescence of Bis(di-tert-butylphenanthroline) Cu(I): a complex with unique reactivity and applications in solar cells
Green Careers Panel Discussion
